Gas challenge-blood oxygen level dependent (BOLD) MRI in monitoring tumor angiogenesis of a rodent Novikoff hepatoma model
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چکیده
to tumor R2* change. A significant positive correlation observed for tumor microvessel density (r = 0.902, p = 0.003) and inverse correlation observed for tumor size (r = -0.802, p = 0.017). Fig. 2 CD34 staining showing diffuse positive CD34 expression (stained brown, left) and color differentiation of CD34 (black, right) for quantification of tumor microvessel density. Fig. 1 MGRE images (left, TE=12ms) and corresponding ΔR2* maps (right, scale 1/s) for 2 N1-S1 hepatoma (arrow) Gas challenge-blood oxygen level dependent (BOLD) MRI in monitoring tumor angiogenesis of a rodent Novikoff hepatoma model
منابع مشابه
Gas-Challenge Blood Oxygen Level Dependent (BOLD) MRI for quantitative assessment of tumor necrosis in rodent hepatoma model
[1]. Forner A et al. Cancer 2009; 115:616-623. [2]. Thomas CD et al. MAGMA 2004; 17:271-280. [3]. Baudelet C et al. Magn Reson Med 2006; 56:1041-1049. [4]. Hoskin PJ et al. Int J Radiat Oncol Biol Phys 2007; 68:1065-1071. [5]. Henning EC et al. Magn Reson Med 2007; 57:501-512. [6]. Deng J et al. J Magn Reson Imaging 2008; 27:1069-1076. Fig. 1 Full FOV absolute T2* change maps (arrow, tumor )(a)...
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